Watch LIVE: Stand Up To Cancer

Michael C. Hall and Christina Applegate at the 2010 Stand Up 2 Cancer event. (Craig Sjodin/ABC via Getty Images)

Watch a live stream of the Stand Up to 2 Cancer event, a one-hour special from 8 to 9 pm EST/ 5 to 6 pm PST featuring Gwyneth Paltrow, Julia Roberts, Matt Damon, Michael Douglas, Jessica Biel, Samuel L. Jackson, Jeremy Renner, Seth Rogen, Emma Stone, Taylor Swift, Coldplay, Alicia Keys, Tim McGraw and SU2C co-founder Katie Couric.

The event, produced this year by Paltrow and Joel Gallin, has raised more than $180 million for cancer research since 2008.

According to SU2C, one in two men and one in three women will be diagnosed with cancer in their lifetime. The reality: the disease touches almost everyone.

This nationally televised fundraising event will air commercial–free on all the major networks (ABC, FOX, NBC and CBS) as well as cable networks (BIO, E!, ENCORE, HBO, HBO Latino, ION Television, Lifetime Movie Network, Logo, MLB Network, mun2, Palladia, SHOWTIME, Smithsonian Channel, STARZ, STYLE, TBS and VH1).

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