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Best Career Comebacks

6 of 26

Neil Patrick Harris

Child star Neil Patrick Harris seemed to be doomed to forever being known as "Doogie Howser," but a deranged cameo in the stoner comedy "Harold and Kumar Go to White Castle," showed audiences--and Hollywood--that he was more than just the Doog. Harris now stars in the hit sitcom "How I Met Your Mother." (Photo by Kevin Winter/Getty Images)

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