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Best NFL Regular Season Matchups to Watch, Week-by-Week

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Week 6: Giants at 49ers – Sunday, Oct. 14 (4:15 p.m.)

The Giants overtime win in the NFC Championship game still stings by the Bay. It was one of the better games of last season’s playoffs and there’s little reason to suspect the rematch will be any less palpitating.

(AP Photo/David J. Phillip)

The opinions expressed are solely those of the author and do not necessarily reflect the views of Comcast.

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