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Best March Madness Upsets

19 of 20

No. 13 Siena Routs No. 4 Vanderbilt

In 2008, the Siena Saints upset the Vanderbilt Commodores, 83-62, in the first round of the tournament. Junior Kenny Hasbrouck led the Saints with 30 points, while senior Tay Fisher contributed by hitting six 3-pointers. (AP Photo/John Raoux)

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